Sega Mega Drive Mini lanserades den 19 september till ett pris om 899 kronor. Nedan följer en lista på de spel som finns på maskinen:
- Alex Kidd in the Enchanted Castle
- Alisia Dragoon
- Altered Beast
- Beyond Oasis
- Castle of Illusion Starring Mickey Mouse
- Castlevania: Bloodlines
- Columns
- Comix Zone
- Contra: Hard Corps
- Darius
- Dr. Robotnik’s Mean Bean Machine
- Dynamite Headdy
- Earthworm Jim
- Ecco the Dolphin
- Eternal Champions
- Ghouls ’n Ghosts
- Golden Axe
- Gunstar Heroes
- Kid Chameleon
- Landstalker
- Light Crusader
- Mega Man: The Wily Wars
- Monster World 4
- Phantasy Star 4: The End of the Millennium
- Road Rash 2
- Shining Force
- Shinobi 3
- Sonic the Hedgehog
- Sonic the Hedgehog 2
- Sonic the Hedgehog Spinball
- Space Harrier 2
- Street Fighter 2: Special Champion Edition
- Streets of Rage 2
- Strider
- Super Fantasy Zone
- Tetris
- Thunder Force 3
- ToeJam & Earl
- Vectorman
- Virtua Fighter 2
- Wonder Boy in Monster World
- World of Illusion Starring Mickey Mouse and Donald Duck
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